产品货号：
GS4552
中文名称：
重组人IFN-ω
英文名称：
Recombinant Human Interferon-Omega
产品规格：
20μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 20.0kDa,containing 172 amino acid residues with two conserved disulfide bonds.
储存条件：冷冻（-20℃）
概述
Interferon-Omega(IFN-ω)coded by IFNW1 gene in human,is a number of the type I interferon family,which includes IFN-α,IFN-β,and IFN-ω.The IFNAR-1/IFNAR-2 receptor complex can help with the signal transduction,followed the antiviral or the antiproliferative actions.IFN-ω is derived from IFN-α/β and share 75%sequence with IFN-α.It has two intramolecular disulfide bonds which are crucial for activities.Mire-Sluis et al have described bioassays for IFN-α,IFN-β,and IFN-ω that exploit the ability of these factors to inhibit proliferation of TF-1 cells induced by GM-CSF.The bioassays can be used also with Epo and TF-1 cells,or Epo and Epo-transfected UT-7 cells.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人IFN-ω，IFN-ω, Human，Recombinant Human Interferon-Omega
储存条件：冷冻（-20℃）
概述
Interferon-Omega(IFN-ω)coded by IFNW1 gene in human,is a number of the type I interferon family,which includes IFN-α,IFN-β,and IFN-ω.The IFNAR-1/IFNAR-2 receptor complex can help with the signal transduction,followed the antiviral or the antiproliferative actions.IFN-ω is derived from IFN-α/β and share 75%sequence with IFN-α.It has two intramolecular disulfide bonds which are crucial for activities.Mire-Sluis et al have described bioassays for IFN-α,IFN-β,and IFN-ω that exploit the ability of these factors to inhibit proliferation of TF-1 cells induced by GM-CSF.The bioassays can be used also with Epo and TF-1 cells,or Epo and Epo-transfected UT-7 cells.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a chemotaxis bioassay using human TF-1 cells is less than 0.01ng/ml,corresponding to a specific activity of>1.0×108 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rHuIFN-ω as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS |
相关搜索：重组人IFN-ω，IFN-ω, Human，Recombinant Human Interferon-Omega